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RNA Sequencing of Solid and Cystic Lesions of the Pancreas


2012-12


2017-12


2019-12


72

Study Overview

RNA Sequencing of Solid and Cystic Lesions of the Pancreas

The nature of cysts and solid masses in the pancreas can be difficult to diagnose. They may be benign, precancerous, or cancer. Current tests such as cytology (looking under a microscope) and tumor markers do not always give us the answer. The investigators are looking for genetic markers on biopsy specimens from the pancreas that will give us a better test for diagnosis. This study is only for diagnosing these lesions. The investigators are not treating any patients.

N/A

  • Pancreas Cyst
  • Pancreas Mass
  • PROCEDURE: pancreas biopsy
  • IRB8317

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates Results Reporting Dates Study Record Updates

2013-03-06  

N/A  

2020-01-07  

2013-03-07  

N/A  

2020-01-10  

2013-03-08  

N/A  

2020-01  

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Design Details

Primary Purpose:
N/A


Allocation:
N/A


Interventional Model:
N/A


Masking:
N/A


Arms and Interventions

Participant Group/ArmIntervention/Treatment
: pancreas cysts and solid masses

patents referred for solid and cystic lesions of the pancreas who will have a biopsy for usual medical care.

PROCEDURE: pancreas biopsy

  • patients who are already having a pancreas biopsy will be invited to enroll. After obtaining enough tissue for usual medical care, we will divert some tissue for the study.
Primary Outcome MeasuresMeasure DescriptionTime Frame
Gene classifier that will classify lesions as benign or malignant with 95% certainty2 years
Secondary Outcome MeasuresMeasure DescriptionTime Frame

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person’s general health condition or prior treatments.

Ages Eligible for Study:
ALL

Sexes Eligible for Study:
18 Years

Accepts Healthy Volunteers:

    Inclusion Criteria:

  • greater than 18 years old,
  • not pregnant,
  • referred for endoscopic ultrasound,
  • have a cyst or mass of the pancreas needing diagnosis.

  • Exclusion Criteria:

  • pregnant,
  • less than age 18,
  • no mass or cyst found.

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

  • Providence Health & Services

  • PRINCIPAL_INVESTIGATOR: Sarah Rodriguez, MD, Oregon Health and Science University

Publications

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

No publications available