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Proteomic Analysis of HLA Complex in Solid Cancers: Breast, Ovary, Colon, Rectum, Stomach, and Pancreas


2007-02


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Study Overview

Proteomic Analysis of HLA Complex in Solid Cancers: Breast, Ovary, Colon, Rectum, Stomach, and Pancreas

The purpose of this study is to evaluate the presence of proteins in solid tumors which may lead to an immune response

The main objective of the study is to evaluate which proteins are presented by the HLA complex of solid tumors. Secondary objectives include to evaluate whether an immune response specific to these proteins has actually been provoked and whether there is a similar immune response following recurrence. Real specimens will be evaluated using PCR and mass spectrometry.

  • Colorectal Neoplasms
  • Stomach Neoplasms
  • Pancreatic Neoplasms
  • Breast Neoplasms
  • Ovarian Cancer
    • ProtHYMC

    Study Record Dates

    These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

    Study Registration Dates Results Reporting Dates Study Record Updates

    2007-01-05  

    N/A  

    2007-01-05  

    2007-01-05  

    N/A  

    2007-01-08  

    2007-01-08  

    N/A  

    2007-01  

    Study Plan

    This section provides details of the study plan, including how the study is designed and what the study is measuring.

    Design Details

    Primary Purpose:
    N/A


    Allocation:
    N/A


    Interventional Model:
    N/A


    Masking:
    N/A


    Arms and Interventions

    Participant Group/ArmIntervention/Treatment
    Secondary Outcome MeasuresMeasure DescriptionTime Frame

    Contacts and Locations

    This section provides the contact details for those conducting the study, and information on where this study is being conducted.

    Study Contact

    Name: Itamar Ashkenazi, M.D.

    Phone Number: 972-4-6304761

    Email: i_ashkenazi@yahoo.com

    Participation Criteria

    Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person’s general health condition or prior treatments.

    Ages Eligible for Study:
    ALL

    Sexes Eligible for Study:

    Accepts Healthy Volunteers:

      Inclusion Criteria:

    • Patients with adenocarcinoma of breast, colon, rectum, ovary , stomach, pancreas

    • Exclusion Criteria:

    • Withdrawal of consent
    • Small specimen which does not allow to retrieve tissue without interfering with pathologic evaluation

    Collaborators and Investigators

    This is where you will find people and organizations involved with this study.

    • Technion, Israel Institute of Technology

    • PRINCIPAL_INVESTIGATOR: Itamar Ashkenazi, M.D., Hillel Yaffe Medical Center

    Publications

    The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

    General Publications

    No publications available