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Using Digestive Microbial Information to Enhance the Early Detection of Pancreatic Cancer


2020-09-01


2023-12-30


2023-12-30


100

Study Overview

Using Digestive Microbial Information to Enhance the Early Detection of Pancreatic Cancer

Pancreatic cancer (PCA) is a leading death-related cancer. There is an urgent need for accurate, noninvasive diagnostic options in the early detection of pancreatic cancer (PCA), since delayed diagnosis increases the risk of metastasis and recurrence. In this study, by analyzing gut and fecal microbial data among the pancreatic versus healthy populations, we aim to establish an early detection tool to improve PCA detection, and to explore potential diagnostic biomarkers.

N/A

  • Pancreatic Cancer
  • OTHER: Oral and Fecal Sample Collection
  • PUMCH-PCAMicrobe-1

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates Results Reporting Dates Study Record Updates

2023-01-09  

N/A  

2023-01-09  

2023-01-09  

N/A  

2023-01-18  

2023-01-18  

N/A  

2023-01  

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Design Details

Primary Purpose:
N/A


Allocation:
N/A


Interventional Model:
N/A


Masking:
N/A


Arms and Interventions

Participant Group/ArmIntervention/Treatment
: PCA

pancreatic cancer patients

OTHER: Oral and Fecal Sample Collection

  • No interventions
: NC

normal control

OTHER: Oral and Fecal Sample Collection

  • No interventions
Primary Outcome MeasuresMeasure DescriptionTime Frame
microbial features by 16s rRNA sequencingwithin 180 days
Secondary Outcome MeasuresMeasure DescriptionTime Frame

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person’s general health condition or prior treatments.

Ages Eligible for Study:
ALL

Sexes Eligible for Study:

Accepts Healthy Volunteers:
1

    Inclusion Criteria:
    PCA Newly diagnosed pancreatic cancer patients; No symptoms of jaundice; Did not yet receive any treatment
    NC Individuals who were undergoing routine screenings or physical examination
    Exclusion Criteria:

Collaborators and Investigators

This is where you will find people and organizations involved with this study.


    • PRINCIPAL_INVESTIGATOR: Menghua Dai, MD, Peking Union Medical College Hospital

    Publications

    The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

    General Publications

    No publications available