Clinical Trial Record

Return to Clinical Trials

Multimodal Therapy Impact on Pancreatic Cancer Survival


2011-01-03


2025-04-30


2025-04-30


405

Study Overview

Multimodal Therapy Impact on Pancreatic Cancer Survival

The goal of this retrospective cohort study is to analyze change of treatment strategies affect the survival outcomes in patients of pancreatic cancer who received curative-intent treatment. The main question it aims to answer is: Hypothesis: Change of treatment strategies involving increased utility of neoadjuvant chemotherapy and aggressive surgical approaches of extended pancreatectomy improved the overall and progression free survival in the patients with pancreatic cancer. Participants received curative treatment for pancreatic cancer.

This study is to analyze the change of treatment strategies and shift of the paradigm over time in a single center. Researchers plan to see the impact of the evolvement to the survival outcomes in pancreatic cancer.

  • Pancreatic Cancer
  • Neoadjuvant Chemotherapy
  • Pancreatectomy
    • NCKUH-11405009

    Study Record Dates

    These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

    Study Registration Dates Results Reporting Dates Study Record Updates

    2025-04-14  

    N/A  

    2025-04-21  

    2025-04-14  

    N/A  

    2025-04-24  

    2025-04-22  

    N/A  

    2025-04  

    Study Plan

    This section provides details of the study plan, including how the study is designed and what the study is measuring.

    Design Details

    Primary Purpose:
    N/A


    Allocation:
    N/A


    Interventional Model:
    N/A


    Masking:
    N/A


    Arms and Interventions

    Participant Group/ArmIntervention/Treatment
    : Group A

    The patient of pancreatic cancer, who began to have treatment in the period between 2011 to 2017.

    : Group B

    The patient of pancreatic cancer, who began to have treatment in the period between 2018 to 2022.

    Primary Outcome MeasuresMeasure DescriptionTime Frame
    Overall survival and Progression-free survivalOverall survival was calculated from the first treatment day of the disease to the day of mortality. Progression-free survival was calculated from the first treatment day of the disease to the day of proression or recurrece of pancreatic cancer.From enrollment to two years after the end of treatment
    Secondary Outcome MeasuresMeasure DescriptionTime Frame

    Contacts and Locations

    This section provides the contact details for those conducting the study, and information on where this study is being conducted.

    Participation Criteria

    Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person’s general health condition or prior treatments.

    Ages Eligible for Study:
    ALL

    Sexes Eligible for Study:
    18 Years

    Accepts Healthy Volunteers:

      Inclusion Criteria:

    • Pancreatic adenocarcinoma
    • Received curative surgery

    • Exclusion Criteria:

    • Other subtypes of pancreatic cancer including acinar cell carcinoma, mucinous carcinoma, undifferentiated carcinoma and intraductal papillary mucinous neoplasm with associated adenocarcinoma
    • Cases with palliative or R2 resection were also excluded from the analysis.

    Collaborators and Investigators

    This is where you will find people and organizations involved with this study.


      • STUDY_CHAIR: Yan-Shen Shan, MD., PhD., Department of Surgery, National Cheng Kung University Hospital

      Publications

      The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

      General Publications

      No publications available