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Establishment of Radiomics Database by Clinical Application of Multiparametric MRI Based on Incoherent Undersampling


2016-11-28


2022-12


2023-11


29

Study Overview

Establishment of Radiomics Database by Clinical Application of Multiparametric MRI Based on Incoherent Undersampling

This study aims to establish radiomics database for pancreas cancer from multiparametric MRI including DCE-MRI obtained by using incoherent undersampling and radial acquisition for clinical staging as well as quantitative analysis.

N/A

  • Pancreas Cancer
  • PROCEDURE: multi-parametric MRI
  • 2015-1160

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates Results Reporting Dates Study Record Updates

2016-10-24  

N/A  

2021-12-16  

2016-10-24  

N/A  

2021-12-17  

2016-10-25  

N/A  

2021-12  

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Design Details

Primary Purpose:
N/A


Allocation:
N/A


Interventional Model:
N/A


Masking:
N/A


Arms and Interventions

Participant Group/ArmIntervention/Treatment
Primary Outcome MeasuresMeasure DescriptionTime Frame
T-stagingT-staging of the tumor at MRI.4 weeks after MR acquisition
Secondary Outcome MeasuresMeasure DescriptionTime Frame
N-stagingN-staging of the tumor at MRI4 weeks after MR acquisition
arterial blood flowarterial blood flow of the tumor and adjacent parenchma on DCE-MRI4 weeks after MR acquisition
arterial fractionarterial fraction of the tumor and adjacent parenchyma on DCE-MRI4 weeks after MR acquisition
mean transit timemean transit time of the tumor and adjacent parenchyma on DCE-MRI4 weeks after MR acquisition
extracellular volumeextracellular volume of the tumor and adjacent parenchyma on DCE-MRI4 weeks after MR acquisition
true diffusiontrue diffusion of the tumor and adjacent parenchyma on DWI with intravoxel incoherent motion model4 weeks after MR acquisition
pseudodiffusionpseudodiffusion of the tumor and adjacent parenchyma on DWI with intravoxel incoherent motion model4 weeks after MR acquisition
perfusion fractionperfusion fraction of the tumor and adjacent parenchyma on DWI with intravoxel incoherent motion model4 weeks after MR acquisition
kurtosiskurtosis of the tumor and adjacent parenchyma on DWI with kurtosis model4 weeks after MR acquisition
mean diffusivitymean diffusivity of the tumor and adjacent parenchyma on DWI with kurtosis model4 weeks after MR acquisition

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person’s general health condition or prior treatments.

Ages Eligible for Study:
ALL

Sexes Eligible for Study:
18 Years

Accepts Healthy Volunteers:

    Inclusion Criteria:

  • surgical candidate for pancreatico-duodenectomy
  • characteristic finding of pancreatic adenocarcinoma on prior CT or MRI
  • OR histologically diagnosed with pancreatic adenocarcinoma
  • signed for informed consent

  • Exclusion Criteria:

  • under 18 years
  • not eligible for pancreatico-duodenectomy
  • unresectable patients (locally advanced on prior CT/MRI or metastatic disease)
  • tumors with suspicion of other histologic types (neuroendocrine, IPMN, etc)
  • any contra-indication of contrast-enhanced MRI
  • recurred pancreatic cancer

Collaborators and Investigators

This is where you will find people and organizations involved with this study.


    • PRINCIPAL_INVESTIGATOR: Jeong Min Lee, MD, Seoul National University Hospital

    Publications

    The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

    General Publications

    No publications available