Blood Collection From Individuals With Lung Disease For Genetic Studies

Study Overview

Blood Collection From Individuals With Lung Disease for Genetic Studies

This is a research study where researchers are collecting blood to evaluate the genetic characteristics of individuals with chronic lung diseases, including asthma, chronic obstructive pulmonary disease (COPD), interstitial lung disease, cystic fibrosis, and lung cancer.

The investigators hope to be able to identify an association between a genetic make-up in the blood samples and the risks of developing a particular lung disease, or severity of a lung disease. The findings of this study might be important to develop future preventative methods and potential treatments for the management of lung disease. The investigators aim to collect blood samples from 300 people with lung disease and 300 controls over 5 years.

Asthma
COPD
Interstitial Lung Disease
Cystic Fibrosis
Lung Cancer

0508008095

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates	Results Reporting Dates	Study Record Updates
First Submitted 2006-08-08	Results First Submitted N/A	Last Update Submitted that met QC Criteria 2016-04-28
First Submitted that Met QC Criteria 2006-08-08	Results First Submitted that Met QC Criteria N/A	Last Update Posted (ESTIMATED) 2016-04-29
First Posted (ESTIMATED) 2006-08-10	Results First Posted N/A	Last Verified 2016-04

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Design Details

Primary Purpose:
N/A

Allocation:
N/A

Interventional Model:
N/A

Masking:
N/A

Arms and Interventions

Participant Group/Arm	Intervention/Treatment
: 1: Lung Disease Individuals with at least one of the following: (1)symptoms consistent with pulmonary disease; (2) chest X-ray consistent with lung disease; (3) pulmonary function tests consistent with lung disease; (4) lung biopsy consistent with lung disease; (5) famil
: 2: Normal Controls Individuals without a history of lung disease

Primary Outcome Measures	Measure Description	Time Frame
Establish a set of normal ranges for various parameters in healthy individual specimens and compare to specimens from individuals with lung disease to determine parameters resulting in disease susceptibility and severity.		5 years

Secondary Outcome Measures	Measure Description	Time Frame

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person’s general health condition or prior treatments.

Ages Eligible for Study:
ALL

Sexes Eligible for Study:
18 Years

Accepts Healthy Volunteers:
1

Must provide informed consent
Males and females, age 18 years and older
Lung disease proven by at least one of the following:

symptoms consistent with pulmonary disease
chest X-rays consistent with lung disease
pulmonary function tests consistent with lung disease
lung biopsy consistent with lung disease
family history of lung disease
disease of organs with know associated with lung disease
individuals suspected of history of lung disease based on history and/or physical examination
normal controls (individuals without history of lung disease) to be sampled to provide a comparison to the lung disease cohort.

Drug and/or alcohol abuse within the past six months
Females who are pregnant or nursing

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Investigators

PRINCIPAL_INVESTIGATOR: Ronald G Crystal, MD, The New York Presbyterian Hospital -- Weill Medical College of Cornell University

Publications

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

No publications available

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Resources

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Caregivers

Clinical Trial Record