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2022-12-20
2027-12-20
2028-12-20
3000
NCT05724992
Associazione Italiana per lo Studio del Pancreas
Associazione Italiana per lo Studio del Pancreas
INTERVENTIONAL
Familial Pancreatic Cancer PROPHilation Program in Italy
The goal of the PROPH-ITA Study is to perform genetic testing in family members of pancreatic cancer patients who may have a genetic predisposition. The subjects belong to the Italian Registry of Families At Risk of Pancreatic Cancer (IRFARPC, #NCT04095195). This investigational study will assess the genetic background of subjects with familiarity with pancreatic cancer only. Participants may accept to undergo genetic testing as part of the IRFARPC registry, through a saliva-swab-based 41-gene panel test. Up to 3,000 participants will be enrolled in this study.
N/A
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
| Study Registration Dates | Results Reporting Dates | Study Record Updates |
|---|---|---|
2022-12-20 | N/A | 2023-02-13 |
2023-02-02 | N/A | 2023-02-15 |
2023-02-13 | N/A | 2023-02 |
This section provides details of the study plan, including how the study is designed and what the study is measuring.
Primary Purpose:
Other
Allocation:
Na
Interventional Model:
Single Group
Masking:
None
Arms and Interventions
| Participant Group/Arm | Intervention/Treatment |
|---|---|
| OTHER: Saliva testing swab Subjects with familiarity with pancreatic cancer enrolled into the IRFARPC registry (NCT04095195) will be submitted to buccal swab for saliva-based genetic testing | GENETIC: Saliva swab testing
|
| Primary Outcome Measures | Measure Description | Time Frame |
|---|---|---|
| Presence - absence of predisposing mutations | Prevalence of genetic mutations over the total tested | 5 years |
| Secondary Outcome Measures | Measure Description | Time Frame |
|---|---|---|
| Correlation of genetic mutations with personal oncological history | Correlation between presence of predisposing mutation and prevalence of cancers | 5 years |
| Correlation of genetic mutations with familial oncological history | Correlation between presence of predisposing mutation and prevalence of cancers in the family | 5 years |
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
|
Study Contact Name: Erica Secchettin, PharmD Phone Number: 0458126254 Email: familiarita.aisp@gmail.com |
Study Contact Backup Name: AISP Association Phone Number: 340 2713112 Email: aisp.ricerca@gmail.com |
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person’s general health condition or prior treatments.
Ages Eligible for Study:
ALL
Sexes Eligible for Study:
18 Years
Accepts Healthy Volunteers:
This is where you will find people and organizations involved with this study.
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
General Publications
No publications available
NPCF was founded on May 29, 2009 and is a 501(c)(3) organization. All donations are tax deductible.
The information and services provided by the National Pancreatic Cancer Foundation are for informational purposes only. The information and services are not intended to be substitutes for professional medical advice, diagnosis or treatment. The National Pancreatic Cancer Foundation does not recommend nor endorse any specific physicians, products or treatments even though they may be mentioned on this site.
